Educational content on VJDementia is intended for healthcare professionals only. By visiting this website and accessing this information you confirm that you are a healthcare professional.

Share this video  

AAN 2025 | The future of biomarkers in dementia diagnosis and the role of tau-PET imaging

Marina Scop Medeiros, MD, University of Pittsburgh, Pittsburgh, PA, discusses the future of biomarkers in dementia diagnosis, highlighting the pivotal role of tau-PET imaging. She explains that tau-PET imaging offers a spatial paradigm of tau distribution in the brain, which correlates better with biological staging. This interview took place at the 77th American Academy of Neurology (AAN) Annual Meeting in San Diego, CA.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Transcript

I see them being incorporated into clinical practice and that would give dementia care a great benefit with more accurate diagnosis. But I do see an important role for tau-PET imaging compared to the plasma or the CSF biomarkers because it gives us the spatial paradigm of where the tau is in the brain, not only the magnitude and that would correlate better with biological staging. And that would probably be the gold standard, even when people try to use different plasma biomarkers to try and predict the biological staging, they would be using the tau-PET as a gold standard...

I see them being incorporated into clinical practice and that would give dementia care a great benefit with more accurate diagnosis. But I do see an important role for tau-PET imaging compared to the plasma or the CSF biomarkers because it gives us the spatial paradigm of where the tau is in the brain, not only the magnitude and that would correlate better with biological staging. And that would probably be the gold standard, even when people try to use different plasma biomarkers to try and predict the biological staging, they would be using the tau-PET as a gold standard. And that’s how I see the future of biomarkers.

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

Read more...