So the new Alzheimer’s Association work group criteria, they suggest four consecutive biological stages of AD with the use of a core biomarker such as amyloid PET and then additional use of tau PET imaging to separate four different groups. The first group would be the people who are only amyloid positive and tau negative. The second group would be the people who are amyloid positive and tau positive only in the medial temporal lobe...
So the new Alzheimer’s Association work group criteria, they suggest four consecutive biological stages of AD with the use of a core biomarker such as amyloid PET and then additional use of tau PET imaging to separate four different groups. The first group would be the people who are only amyloid positive and tau negative. The second group would be the people who are amyloid positive and tau positive only in the medial temporal lobe. The third group, second to last, is the people who are tau positive in the neocortical region with a moderate uptake of tau. The fourth and last group is the people who are amyloid positive and tau positive also in the neocortical region but with a higher uptake.
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