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AAIC 2026 | Strategies for implementing brain health and AD risk-reduction in low- and middle-income countries

Lucia Crivelli, PhD, Fleni, Buenos Aires, Argentina, comments on the implementation of brain health and Alzheimer’s disease (AD) risk-reduction strategies in low- and middle-income countries, emphasizing the importance of community engagement and feasibility. Dr Crivelli highlights the intervention used in the LatAm FINGERS trial (NCT06492967), noting the need to strike a balance between a systematic, structured approach and one that is practical and feasible to implement within the community. This interview took place at the 2026 Alzheimer’s Association International Conference (AAIC) in London, UK.

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Transcript

Regarding strategies for implementing brain health in low- and middle-income countries, what I can say is that you need to work locally in the communities, that you need to hear the community, to listen to the community. You cannot go design something and impose it on the population. So the idea is to listen to the community and the stakeholders that will receive it and to see what is feasible there...

Regarding strategies for implementing brain health in low- and middle-income countries, what I can say is that you need to work locally in the communities, that you need to hear the community, to listen to the community. You cannot go design something and impose it on the population. So the idea is to listen to the community and the stakeholders that will receive it and to see what is feasible there. Again, feasibility is a big issue here. And also to get out of the clinical trial toolbox. It’s not about applying the same principles in research that you do in the community. Research is like a laboratory when you do everything perfectly and you get the higher effects we saw in this intervention that we had effects only with regular health advice and we had bigger effects with a systematic intervention, then we have to find a place in the middle in which something can be implemented, but the most important thing is to listen to the community, to talk to other leaders, to regional leaders, to politicians, to people who are experts in healthcare policy, and not to be a researcher that tries to replicate their lab in the community.

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