Carla Abdelnour, PhD, Stanford University, Palo Alto, CA, discusses the importance of accounting for co-pathologies during clinical trials, particularly the co-pathologies of dementia with Lewy bodies (DLB) and Alzheimer’s disease. DLB is characterized by Lewy pathology but is commonly found to coexist with Alzheimer’s disease, as well as other co-morbidities. Dr Abdelnour advocates for greater accountability for co-pathologies in the design of clinical trials and the selection of participants, to allow for personalized therapies. Furthermore, she supports the inclusion of biofluid biomarkers to assist in the development of disease modifying therapies for DLB. This interview took place at the Alzheimer’s Association International Conference® (AAIC) 2023 in Amsterdam, Netherlands.
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