With the recent approval of lecanemab for the treatment of Alzheimer’s disease (AD) by the US Food and Drug Administration (FDA), there is now a push for earlier diagnosis and identification of patients at risk of developing AD. Alvaro Pascual-Leone, MD, PhD, Wolk Center for Memory Health, Hebrew SeniorLife & Harvard Medical School, Boston, MA; Linus Health, CMO, presents Linus Health’s digital brain health platform, designed to facilitate the early detection of AD by primary healthcare providers, thus enabling intervention as early as possible. The platform incorporates a number of screening tools that can quickly identify patients with or at risk of developing mild cognitive impairment (MCI) and in doing so, reduce some of the burden on healthcare providers. This interview took place at the Clinical Trials on Alzheimer’s Disease Congress 2022 in San Francisco.
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Dr. A. Pascual-Leone is a co-founder and the chief medical officer of Linus Health. He is co-founder of TI solutions and serves as a paid member of the scientific advisory boards for Neuroelectrics, Magstim Inc., TetraNeuron, Skin2Neuron, MedRhythms, and Hearts Radiant. Dr. A. Pascual-Leone is partly supported by grants from the National Institutes of Health and BrightFocus Foundation. Dr. A Pascual-Leone is listed as an inventor on several issued and pending patents on the real-time integration of transcranial magnetic stimulation with electroencephalography and magnetic resonance imaging, and applications of noninvasive brain stimulation in various neurological disorders, as well as digital biomarkers of behavior.