AAN 2026 | Convergent causal mapping of memory to identify brain stimulation targets for memory dysfunction

Calvin Howard, MD, Harvard Medical School, Boston, MA, discusses the concept of convergent causal mapping of memory, highlighting that various brain lesions or stimulation sites converge upon a common underlying brain network involved in memory. Dr Howard explains that this network includes regions such as the precuneus, mesial frontal lobe, and mesial temporal lobe, and that connectivity to this network can better explain variance and predict outcomes in memory-related studies, including those on Alzheimer’s disease. This interview took place at the 78th American Academy of Neurology (AAN) Annual Meeting in Chicago, IL.

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