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AD/PD 2024 | Distinguishing between late-onset primary psychiatric disorders and dementia

Jenna Najar, MD, PhD, Sahlgrenska University Hospital, Gothenburg, Sweden & Amsterdam University Medical Center, Amsterdam, Netherlands, delves into research focusing on the relationship between late-onset neuropsychiatric symptoms and dementia. Challenges can arise because patients with neurodegenerative disorders often display neuropsychiatric symptoms, leading to misdiagnosis of dementia as a primary psychiatric disorder. Research is now focusing on biomarkers to differentiate between late-onset psychiatric disorders such as schizophrenia and those with frontotemporal dementia. Dr Najar is looking into genetic factors to enhance diagnostics and understand the genetic architecture of these disorders. Studies are also investigating polygenic risk scores for distinguishing diagnoses, potentially working alongside other measures in diagnosis. This interview took place at the AD/PD™ 2024 congress in Lisbon, Portugal.

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