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AD/PD 2023 | Unravelling sex and gender differences in brain and mental diseases

Antonella Chadha Santuccione, MD, co-founder and CEO of the Women’s Brain Project and the CMO at Altoida Inc., shares the goals and work of the Women’s Brain Project (WBP). The WBP is an international, non-profit organization established in 2017, which aims to transform the state of drug development and treatment for brain and mental disease through sex and gender factors as a gateway to precision medicine. They work on all aspects of medicine and care, from basic science research and developing novel technologies, to engaging with regulators and advocating for change. Dr Chadha Santuccione highlights several key projects from the past year, including the first ever Alzheimer’s disease patient journey analysis from a sex and gender standpoint. Preliminary results have shown key differences in diagnostic pathways between males and females. The WBP has also recently published on the economic rationale for investing in sex and gender-specific research, in collaboration with Economist Impact. By highlighting the cost of missing sex and gender factors to drug developers and healthcare systems, they emphasize the importance prioritizing its incorporation into research. This interview took place at the AD/PD™ 2023 congress in Gothenburg, Sweden.

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