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AAIC 2026 | Investing in prevention strategies to reduce the long-term economic burden of dementia

Richard Dodel, MD, University of Duisburg-Essen, Essen, Germany, emphasizes the importance of investing in prevention strategies to reduce the long-term economic burden of dementia, highlighting the need to encourage physical exercise and healthy habits in older adults. Prof. Dodel stresses that while epidemiological studies have shown the potential of prevention, more clinical trials are needed to establish a causal relationship between prevention programs and outcomes. This interview took place at the 2026 Alzheimer’s Association International Conference (AAIC) in London, UK.

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Transcript

This is a major issue. I’m a geriatrician. I’m a neurologist and a geriatrician. And from my part, I think what we should invest now and with very major impact is prevention. So what can we do so that the people don’t get into dementia or we can prolong it and there’s a large bunch of knowledge or evidence now out on what we could do with prevention, but it’s not only that we know how to do it, we have to do prevention, yes, and this is especially in the older people, it’s a major issue...

This is a major issue. I’m a geriatrician. I’m a neurologist and a geriatrician. And from my part, I think what we should invest now and with very major impact is prevention. So what can we do so that the people don’t get into dementia or we can prolong it and there’s a large bunch of knowledge or evidence now out on what we could do with prevention, but it’s not only that we know how to do it, we have to do prevention, yes, and this is especially in the older people, it’s a major issue. How do you get someone with 75 who hasn’t done physical training or sports since about 30 years? How do you bring him again into doing sports or doing exercise or whatever? That’s a major problem. So I think this is one major part of the policy people should focus on, but not only for Alzheimer’s disease. I mean, this helps for heart failure. It helps for Parkinson’s disease. It helps for stroke, for cardiac arrest. I mean, it helps for many, many diseases, so I think major investments and major research should go into prevention. We know from many studies, but most studies are epidemiological studies, so there’s not a causal relation between the prevention and what we can prevent and the outcome. So it’s very necessary that we have research on prevention, especially on clinical trials, which evaluate the outcome and the prevention program. From the other points, I mean, it’s very difficult to intervene. I already said that the informal care is important, that we reduce the burden for the families. But there are a number of possibilities how to reduce the burden of the disease. I think that at the moment in the discussion, in the different healthcare programs for dementia, most of the largest countries have a program for dementia, a dementia strategy, and we have to follow them. That’s what is very important.

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