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WCN 2023 | Impact of disease modifying therapy introduction on symptomatic treatment use in Alzheimer’s disease

Paulo Caramelli, MD, PhD, Federal University of Minas Gerais, Belo Horizonte, Brazil, discusses the impact that global introduction of disease modifying therapies (DMTs), such as anti-amyloid therapies, may have on the use of symptomatic treatments, such as cholinesterase inhibitors, which are currently the standard of care in Alzheimer’s disease (AD). Dr Caramelli believes that these two distinct classes of drugs are not mutually exclusive and that they may be used synergistically in future to improve patient outcomes. It is important to continue to utilize cholinesterase inhibitors, alongside novel DMTs, due to the plethora of long-term data on their safety and clinical effects. This interview took place at the World Congress of Neurology (WCN) 2023 in Montreal, Canada.

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Paulo Caramelli reports the following disclosures: Preparation of material for CME and participation as speaker in symposia sponsored by Aché, Roche, and Torrent laboratories. Participation in advisory boards for Aché, Eurofarma, Knight Therapeutics and Roche.