Byron Creese, PhD, of the University of Exeter Medical School, Exeter, UK, discusses the use of later-life onset neuropsychiatric symptoms (NPS) as early clinical markers for dementia. These symptoms include impairments in sleep or mood, as well as signs of depression and agitation. NPS commonly manifest in dementia with a prevalence rate of up to 97% and have therefore been suggested for use within the diagnosis of dementia. The mild behavioral impairment (MBI) diagnostic framework was made to standardize the assessment of NPS and research has shown promising results in its ability to diagnose dementias, though it still requires improvement for use within a clinical setting. This interview took place at the Alzheimer’s Association International Conference® (AAIC) 2023 in Amsterdam, Netherlands.
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