Biology

TREM2 as a target for disease modification in Alzheimer’s disease

Hearing loss and dementia

Connecting diabetes and Alzheimer’s disease

TREM2-targeted antibodies enhance microglial function in Alzheimer’s disease model

Exploring the potential role of amyloid deposition in the gut in Alzheimer’s disease

Improving the next generation of anti-amyloid antibodies: prioritizing selectivity with PMN310

Mechanistic links between depressive symptoms and cognitive deficits

PMN310 anti-amyloid antibody preserves learning and memory in animal models

What causes ARIA in response to Alzheimer’s disease immunotherapy?

Relationship between amyloid and tau modulated by astrocyte reactivity

Obesity and type 2 diabetes cause blood-brain barrier dysfunction and reduced brain blood flow

Help or harm? Targeting the immune system in Alzheimer’s disease

Prioritizing research into obesity and diabetes as dementia risk factors

Underlying mechanisms of vulnerability in early Alzheimer’s disease

Alzheimer’s disease subtypes identified based on blood proteomics

APOEε4 drives Aβ-dependent formation of tau tangles