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AAIC 2023 | Capabilities of 7-Tesla MRI in dementia research

Tamer Ibrahim, PhD, University of Pittsburgh, PA, discusses different facets of 7-Tesla magnetic resonance imaging (7T-MRI) that enhance its usefulness as a tool for understanding dementia, Alzheimer’s disease (AD), and aging. Improved structural imaging of the brain with 7T-MRI allows for better delineation of grey and white matter, visualization and segmentation of perivascular spaces, and study of white matter hyperintensities. This high-resolution imaging also allows us to view connectivity within the brain, observing functionality in vivo during the completion of different tasks, as well as observing fiber connectivity within brain tissue. Finally, fluid dynamics can be analyzed to determine the flow of cerebrospinal fluid (CSF) and blood in real time, an aspect of 7T-MRI that could prove especially useful when looking at the accumulation and clearance of amyloid plaques and tau fibrils. Recorded at the Alzheimer’s Association International Conference (AAIC) 2023 held in Amsterdam, Netherlands.

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