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CTAD 2023 | Fluid biomarkers of tau pathology

Lyduine Collij, PhD, BioFINDER group, Lund University, Lund, Sweden, discusses our current understanding of blood-based tau biomarkers, highlighting research that shows many p-tau variants are likely to be more reflective of amyloid pathology than tau burden. The strong correlation between tau burden and cognition is well recognized. It is therefore important to establish cost effective and accessible biomarkers that are more specific for tau. Dr Collij mentions ongoing research into p-tau205 and MTBR-243 as markers of tau pathology. This interview took place at the CTAD 2023 conference in Boston, MA.

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Dr. Collij has received research support from GE Healthcare and Springer Healthcare (paid by Eli Lilly). Both are paid to instituation. Dr. Collij’s salary is supported by the MSCA Doctoral Fellowship grant (#101108819) and Alzheimer Association Research Fellowship grant (#23AARF-1029663).