George Perry, PhD, University of Texas at San Antonio, San Antonio, TX, discusses unanswered questions in Alzheimer’s disease (AD). With the uncertainty around AD, it is crucial to understand how the condition integrates the aging process and what the precursors are. Current knowledge indicates that AD is not a continuum of normal aging but that a break occurs early in the disease – leading to oxidative stress and mitochondrial changes that occur differently from normal aging. Dr Perry states that discovering the cause of change in brain physiology is crucial in AD research; with the brain altering to a new, non-functional state which deteriorates, researchers are still investigating single causes – when there should be a greater focus on multiple variables co-occurring. This interview took place during the 2022 World Congress on Controversies in Neurology (CONy) meeting.
Disclosures
Synaptogenix –Chair of Scientific Advisory Board and Equity Nervgen—Scientific Advisory Board Neurotez- Equity
