BNA 2023 | Alzheimer’s disease functional genomics with iPSCs

Julia TCW, PhD, Boston University, Chobanian & Avedisian School of Medicine, Boston, MA, shares her thoughts on the need to deepen our understanding of Alzheimer’s disease risk variants in order to develop new therapeutic targets and work towards a precision medicine approach to disease management. Genome wide association studies have expedited Alzheimer’s disease basic research, spotlighting proteins and pathways that may be amenable to intervention. Prof. TCW notes that the next step is to look at how these variants impact individual cell types in a cell autonomous and non-cell-autonomous manner. This interview took place at The BNA 2023 International Festival of Neuroscience in Brighton, UK.

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To contact Prof. TCW: [email protected], [email protected]