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ARUK 2018 | Lothian Birth Cohort 1936: a significant resource for studying lifetime cognition

Studies of cognitive decline typically consist of a cohort of patients with disease vs. healthy age-matched controls; however, there are fewer long-term studies following the progression of a population over their lifetime. Here, Tara Spires-Jones, BA, BSc, MSc, PhD, of the University of Edinburgh, Edinburgh, UK, discusses the story and current utility of the Lothian Birth Cohort 1936, a valuable resource for studying cognition. Prof. Spires-Jones highlights the results observed from the work of her PhD student, Makis Tzioras, which has made use of this cohort to assess amyloid-β, tau and glial features. This video was recorded at the Alzheimer’s Research UK Conference 2018, held in London, UK.