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ARUK 2018 | ApoE4 and clusterin: partners in crime in Alzheimer’s synaptic degeneration

Our knowledge of the underlying biology of Alzheimer’s disease is steadily advancing, with a number of new insights recently. In this exciting interview, Tara Spires-Jones, BA, BSc, MSc, PhD, of the University of Edinburgh, Edinburgh, UK, discusses her group’s work on synaptic degeneration in Alzheimer’s disease, which has uncovered interesting results implicating APOE4 and clusterin. Prof. Spires-Jones highlights the potential impact of these results and the next steps for this field of research. This video was recorded at the Alzheimer’s Research UK Conference 2018, held in London, UK.