Neuropathology is the kind of science in which we look at tissue from the brain, usually donated by people who had a disease or didn’t have but wanted to have their brain studied so we can understand better aging and neurodegenerative diseases. And because we have direct access to tissue, we can see under the microscope exactly what is going on there with a kind of resolution that no other way or discipline can give us...
Neuropathology is the kind of science in which we look at tissue from the brain, usually donated by people who had a disease or didn’t have but wanted to have their brain studied so we can understand better aging and neurodegenerative diseases. And because we have direct access to tissue, we can see under the microscope exactly what is going on there with a kind of resolution that no other way or discipline can give us. So neuropathology is something that exists for more than 100 years, but it came to a point that people felt that we learned everything we had to learn from what we can see under the microscope and we should move on to more modern techniques. And this was true, this was fair. But in the past years, with so many advances in methodology for everything, these methods also came to be used in human tissue. So now we can see under the microscope and using other techniques things that we couldn’t see before. And because the resolution is so much better, it’s guiding us and teaching us what we should be looking at in living patients to predict dementia or maybe to check if our treatments work better. And some of these findings that we are having were not on the radar, so I’m super excited about how it’s helping really to shape the way we are seeing dementia now and in the future.
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