Educational content on VJDementia is intended for healthcare professionals only. By visiting this website and accessing this information you confirm that you are a healthcare professional.

Share this video  

AD/PD 2026 | Representation of diverse populations in AD research

Sid O’Bryant, PhD, Institute for Translational Research at UNT Health, Fort Worth, TX, discusses the importance of representation of diverse populations in Alzheimer’s disease (AD) research. Dr O’Bryant emphasizes the need for a community-based approach, building trust and relationships with communities to increase participation in research programs and ensure that novel therapies and biomarkers are accessible to all. This interview took place at the AD/PD™ 2026 International Conference on Alzheimer’s and Parkinson’s Diseases in Copenhagen, Denmark.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Transcript

Exactly, and that’s really the question. That’s the next to me evolution of where the field needs to be because we’ve done such a wonderful job in building these novel biomarkers and even getting novel therapies out into the clinic. Now what we really have to focus on is how do we get the communities engaged so we have better representation. What I say all the time is there’s precision medicine for no one without adequate representation of everyone...

Exactly, and that’s really the question. That’s the next to me evolution of where the field needs to be because we’ve done such a wonderful job in building these novel biomarkers and even getting novel therapies out into the clinic. Now what we really have to focus on is how do we get the communities engaged so we have better representation. What I say all the time is there’s precision medicine for no one without adequate representation of everyone. So by taking that, what we do is more of a community-based approach so that we engage the community in education by getting those groups involved. And once we see now these different patterns and progression, that’s the key to precision medicine. That’s how we start saying, okay, for this type of individual, it’s amyloid plus tau, so now we know we’re multimodal. For this group, it might be amyloid plus diabetes, and now we need a GLP-1 or something along those lines. For others, it might be depression. So this is, to me, where the field really needs to focus, and things that I’ve talked about before, engaging the community simply takes a different approach. We need to get out of our clinics and more into the community, building community networks and community relationships so we build trust. I have to have the communities trust me before they send their loved ones to me. And so once you do that, however, the whole world changes with who shows up into these research programs. And it’s so rewarding to be able to get out into those communities and see how much they truly want to be involved in the science and the trials and everything, and so that’s what we’ve been working on so hard, and so many others in the community in the field, and that’s the next evolution, that’s what we must do, and that’s the key to precision medicine.

This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.

Read more...